Concepedia

Direct inhibition of caspase 3 is dispensable for the anti‐apoptotic activity of XIAP

John Silke, Paul G. Ekert, Catherine L. Day, Christine J. Hawkins, Manuel Baca, Joanne Chew, Miha Pakusch, Anne M. Verhagen, David L. Vaux

The EMBO Journal · 2001 · 118 citations · 47 references

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Concepts

References

47

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

Peng Li, Deepak Nijhawan, I. Imawati Budihardjo et al. · Cell · 1997 · 7.3K citations · Full text

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The determination of enzyme inhibitor constants

Martin Dixon · Biochemical Journal · 1953 · 4.1K citations · Full text

, , +15

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

Donald W. Nicholson, Ambereen Ali, Nancy A. Thornberry et al. · Nature · 1995 · 4K citations

, , +13

Smac, a Mitochondrial Protein that Promotes Cytochrome c–Dependent Caspase Activation by Eliminating IAP Inhibition

Chunying Du, Min Fang, Yucheng Li et al. · Cell · 2000 · 3.5K citations · Full text

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FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex

Marta Muzio, Arul M. Chinnaiyan, Frank Kischkel et al. · Cell · 1996 · 3.1K citations · Full text

, , +14