Catherine L. Day

Differential Targeting of Prosurvival Bcl-2 Proteins by Their BH3-Only Ligands Allows Complementary Apoptotic Function

Lin Chen, Simon N. Willis, Andrew H. Wei et al. · Molecular Cell · 2005 · 1.8K citations · Full text

Medicine, Apoptosis, Immunology +7

The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized

Mark F. van Delft, Andrew H. Wei, Kylie D. Mason et al. · Cancer Cell · 2006 · 1.2K citations · Full text

Apoptosis, Immunology, Cell Death +4

HtrA2 Promotes Cell Death through Its Serine Protease Activity and Its Ability to Antagonize Inhibitor of Apoptosis Proteins

Anne M. Verhagen, John Silke, Paul G. Ekert et al. · Journal of Biological Chemistry · 2002 · 546 citations · Full text

Structural insights into the degradation of Mcl-1 induced by BH3 domains

Peter E. Czabotar, Erinna F. Lee, Mark F. van Delft et al. · Proceedings of the National Academy of Sciences · 2007 · 437 citations · Full text

Protein Assembly, Apoptosis, Molecular Biology +18

Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans

Katrin Linke, Peter D. Mace, Clyde A. Smith et al. · Cell Death and Differentiation · 2008 · 274 citations · Full text

Engineering, Molecular Biology, Crystallography +2