Concepedia

Simon N. Willis

SN

36

Publications

8.3K

Citations

28

H-Index

1996

Active since

Affiliations

Walter and Eliza Hall Institute of Medical Research(Current)

The University of Melbourne

Harvard University

Yale University

Brigham and Women's Hospital

Simon N. Willis is an author at Walter and Eliza Hall Institute of Medical Research specializing in immunology, medicine, and cell biology.

ORCID

Top concepts

Publications per year

1996–2024

36

Publications

36

Differential Targeting of Prosurvival Bcl-2 Proteins by Their BH3-Only Ligands Allows Complementary Apoptotic Function

Lin Chen, Simon N. Willis, Andrew H. Wei et al. · Molecular Cell · 2005 · 1.8K citations · Full text

, , +7

The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized

Mark F. van Delft, Andrew H. Wei, Kylie D. Mason et al. · Cancer Cell · 2006 · 1.2K citations · Full text

, , +4

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-x <sub>L</sub> , but not Bcl-2, until displaced by BH3-only proteins

Simon N. Willis, Chen Lin, Grant Dewson et al. · Genes & Development · 2005 · 1.2K citations · Full text

Apoptosis Initiated When BH3 Ligands Engage Multiple Bcl-2 Homologs, Not Bax or Bak

Simon N. Willis, Jamie I. Fletcher, Thomas Kaufmann et al. · Science · 2007 · 1.1K citations

, , +11

Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells

Wei Shi, Yang Liao, Simon N. Willis et al. · Nature Immunology · 2015 · 377 citations

, , +9

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