Jamie I. Fletcher

Differential Targeting of Prosurvival Bcl-2 Proteins by Their BH3-Only Ligands Allows Complementary Apoptotic Function

Lin Chen, Simon N. Willis, Andrew H. Wei et al. · Molecular Cell · 2005 · 1.8K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-x _L , but not Bcl-2, until displaced by BH3-only proteins

Simon N. Willis, Grant Dewson, Andrew H. Wei et al. · Genes & Development · 2005 · 1.2K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Apoptosis Initiated When BH3 Ligands Engage Multiple Bcl-2 Homologs, Not Bax or Bak

Simon N. Willis, Jamie I. Fletcher, Thomas Kaufmann et al. · Science · 2007 · 1.1K citations

Life Sciences, Cell Biology, Molecular Biology +15

Programmed Anuclear Cell Death Delimits Platelet Life Span

Kylie D. Mason, Marina R. Carpinelli, Jamie I. Fletcher et al. · Cell · 2007 · 1K citations · Full text

Life Sciences, Cell Biology, Hematology +9

The structure of a novel insecticidal neurotoxin, ω-atracotoxin-HV1, from the venom of an Australian funnel web spider

Jamie I. Fletcher, Ross Smith, Séan O’Donoghue et al. · Nature Structural Biology · 1997 · 192 citations

Life Sciences, Entomology, Toxicology +11