John Silke

Identification of DIABLO, a Mammalian Protein that Promotes Apoptosis by Binding to and Antagonizing IAP Proteins

Anne M. Verhagen, Paul G. Ekert, Miha Pakusch et al. · Cell · 2000 · 2.3K citations · Full text

Protein Function, Autoimmune Disease, Apoptosis +9

The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism

James M. Murphy, Peter E. Czabotar, Joanne M. Hildebrand et al. · Immunity · 2013 · 1.2K citations · Full text

Protein Function, Signal Transduction, Medicine +14

IAP Antagonists Target cIAP1 to Induce TNFα-Dependent Apoptosis

James E. Vince, W. Wei‐Lynn Wong, Nufail Khan et al. · Cell · 2007 · 1.1K citations · Full text

Signal Transduction, Signaling Pathway, Medicine +7

Identification and Validation of Oncogenes in Liver Cancer Using an Integrative Oncogenomic Approach

Lars Zender, Mona S. Spector, Wen Xue et al. · Cell · 2006 · 1.1K citations · Full text

Hepatology, Hepatocellular Carcinoma, Medicine +11

Linear ubiquitination prevents inflammation and regulates immune signalling

Björn Gerlach, Stefanie M. Cordier, Anna C. Schmukle et al. · Nature · 2011 · 912 citations

Inflammation, Immunology, Immune Regulation +5