Concepedia

Parp‐1 protects homologous recombination from interference by Ku and Ligase IV in vertebrate cells

Helfrid Hochegger, Donniphat Dejsuphong, Toru Fukushima, Ciaran G. Morrison, Eiichiro Sonoda, Valérie Schreiber, Guang Zhao, Alihossein Saberi, Mitsuko Masutani, Noritaka Adachi,

The EMBO Journal · 2006 · 269 citations · 41 references

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41

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

Hannah Farmer, Nuala McCabe, Christopher J. Lord et al. · Nature · 2005 · 6.7K citations

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Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

Helen E. Bryant, Niklas Schultz, Huw D. Thomas et al. · Nature · 2005 · 5.2K citations

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Homologous recombination and non‐homologous end‐joining pathways of DNA double‐strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells

Minoru Takata, Masao S. Sasaki, Eiichiro Sonoda et al. · The EMBO Journal · 1998 · 1.2K citations · Full text

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Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells

Josiane Ménissier de Murcia, C. Niedergang, Carlotta Trucco et al. · Proceedings of the National Academy of Sciences · 1997 · 1.1K citations · Full text

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Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia

Mikael J. L. Eliasson, Kenji Sampei, Allen S. Mandir et al. · Nature Medicine · 1997 · 1K citations

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