Concepedia

Coupling of the antennapedia third helix to a potent antagonist of the p53/hdm2 protein–protein interaction

Carlos Garcı́a-Echeverrı́a, Pascal Furet, Patrick Chêne

Bioorganic & Medicinal Chemistry Letters · 2001 · 15 citations · 18 references

DOI

Concepts

References

18

Mdm2 promotes the rapid degradation of p53

Ygal Haupt, Ruth Maya, Anat Kazaz et al. · Nature · 1997 · 4.5K citations

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Regulation of p53 stability by Mdm2

Michael H.G. Kubbutat, Stephen N. Jones, Karen H. Vousden · Nature · 1997 · 3.3K citations

, , +10

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

Jamil Momand, Gerard P. Zambetti, David C. Olson et al. · Cell · 1992 · 3.1K citations

, , +10

Amplification of a gene encoding a p53-associated protein in human sarcomas

Jonathan D. Oliner, Kenneth W. Kinzler, Paul S. Meltzer et al. · Nature · 1992 · 2K citations · Full text

, , +12

Detecting Protein Function and Protein-Protein Interactions from Genome Sequences

Edward M. Marcotte, Matteo Pellegrini, Ho Leung Ng et al. · Science · 1999 · 1.7K citations

, , +15