Protein-Ligand Coupling Optimization is a computational or experimental framework designed to enhance the specificity and efficiency of allosteric communication between a protein and its ligand by systematically refining their interaction interface to achieve desired regulatory outcomes.
3
Publications
50
Citations
27
Authors
8
Institutions
Publications per year
2017–2026
0
Publications
3
Jason Manka, Paige N. Vinson, Karen J. Gregory et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 12 citations · Full text
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Authors
27
- JS
1
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- PJ
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- HU
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- EJ
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- PN
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1–5 of 27
Institutions
8
United States Department of Veterans Affairs
Washington, United States
1 h-index
1 publications
12 citations
Novartis (Switzerland)
Basel, Switzerland
1 h-index
3 publications
45 citations
VA Tennessee Valley Healthcare System
Nashville, United States
1 h-index
1 publications
12 citations
Vanderbilt University Medical Center
Nashville, United States
1 h-index
16 publications
192 citations
Vanderbilt University
Nashville, United States
1 h-index
3 publications
36 citations
Monash University
Melbourne, Australia
1 h-index
1 publications
12 citations
University of Alberta
Edmonton, Canada
1 h-index
3 publications
69 citations
Janssen (Belgium)
Beerse, Belgium
1 h-index
4 publications
48 citations
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Venues
- Bioorganic & Medicinal Chemistry Letters
2 publications · 27 citations
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- Journal of Pharmaceutical Sciences
1 publications · 23 citations
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