Concepedia

Short Hairpin RNA Screen Reveals Bromodomain Proteins as Novel Targets in Acute Myeloid Leukemia

Gerd A. Blobel, Anna Kalota, Patricia Vanessa Sanchez, Martin Carroll

Cancer Cell · 2011 · 23 citations · 9 references

DOIFull text

Open access

Concepts

References

9

Selective inhibition of BET bromodomains

P. Filippakopoulos, Jun Qi, S. Picaud et al. · Nature · 2010 · 4.3K citations · Full text

, , +5

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

Johannes Zuber, Junwei Shi, Eric Wang et al. · Nature · 2011 · 1.9K citations

, , +9

Suppression of inflammation by a synthetic histone mimic

Edwige Nicodème, Kate L. Jeffrey, Uwe Schaefer et al. · Nature · 2010 · 1.6K citations · Full text

, , +12

The Bromodomain Protein Brd4 Is a Positive Regulatory Component of P-TEFb and Stimulates RNA Polymerase II-Dependent Transcription

Moon Kyoo Jang, Kazuki Mochizuki, Meisheng Zhou et al. · Molecular Cell · 2005 · 1.3K citations · Full text

, , +14

Recruitment of P-TEFb for Stimulation of Transcriptional Elongation by the Bromodomain Protein Brd4

Zhiyuan Yang, Jasper H. N. Yik, Ruichuan Chen et al. · Molecular Cell · 2005 · 1.1K citations · Full text

, , +10