Ruichuan Chen

Recruitment of P-TEFb for Stimulation of Transcriptional Elongation by the Bromodomain Protein Brd4

Zhiyuan Yang, Jasper H. N. Yik, Ruichuan Chen et al. · Molecular Cell · 2005 · 1.1K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10

Inhibition of P-TEFb (CDK9/Cyclin T) Kinase and RNA Polymerase II Transcription by the Coordinated Actions of HEXIM1 and 7SK snRNA

Jasper H. N. Yik, Ruichuan Chen, Rieko Nishimura et al. · Molecular Cell · 2003 · 468 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Phosphorylated Positive Transcription Elongation Factor b (P-TEFb) Is Tagged for Inhibition through Association with 7SK snRNA

Ruichuan Chen, Zhiyuan Yang, Qiang Zhou · Journal of Biological Chemistry · 2004 · 166 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

PP2B and PP1α cooperatively disrupt 7SK snRNP to release P-TEFb for transcription in response to Ca²⁺signaling

Ruichuan Chen, Min Liu, Huan Li et al. · Genes & Development · 2008 · 163 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

A Human Immunodeficiency Virus Type 1 Tat-Like Arginine-Rich RNA-Binding Domain Is Essential for HEXIM1 To Inhibit RNA Polymerase II Transcription through 7SK snRNA-Mediated Inactivation of P-TEFb

Jasper H. N. Yik, Ruichuan Chen, Andrea C. Pezda et al. · Molecular and Cellular Biology · 2004 · 124 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +16