Concepedia

Bromodomain Proteins

Bromodomain Proteins is a class of epigenetic reader proteins that specifically recognize and bind to acetylated lysine residues on histone tails, thereby facilitating the recruitment of transcriptional regulatory complexes to chromatin.

1.1K

Publications

93.3K

Citations

7.6K

Authors

1.5K

Institutions

Publications per year

2017–2026

560

Parents

Publications

1.1K

Selective inhibition of BET bromodomains

P. Filippakopoulos, Jun Qi, S. Picaud et al. · Nature · 2010 · 4.3K citations · Full text

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Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family

P. Filippakopoulos, S. Picaud, Maria Mangos et al. · Cell · 2012 · 1.8K citations · Full text

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Phthalimide conjugation as a strategy for in vivo target protein degradation

Georg E. Winter, Dennis L. Buckley, Joshiawa Paulk et al. · Science · 2015 · 1.7K citations

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Structure and ligand of a histone acetyltransferase bromodomain

Christophe Dhalluin, Justin E. Carlson, Lei Zeng et al. · Nature · 1999 · 1.7K citations

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The Bromodomain Protein Brd4 Is a Positive Regulatory Component of P-TEFb and Stimulates RNA Polymerase II-Dependent Transcription

Moon Kyoo Jang, Kazuki Mochizuki, Meisheng Zhou et al. · Molecular Cell · 2005 · 1.3K citations · Full text

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1–5 of 1.1K

Authors

7.6K

  1. SK
    Stefan Knapp

    University of Oxford, United Kingdom

    57 publications · 12.4K citations

    43

    h-index

  2. RK
    Rab K. Prinjha

    GlaxoSmithKline (United Kingdom), United Kingdom

    45 publications · 4K citations

    31

    h-index

  3. JE
    James E. Bradner

    Dana-Farber Cancer Institute, United States

    31 publications · 8.2K citations

    28

    h-index

  4. SM
    Susanne Müller

    University of Oxford, United Kingdom

    29 publications · 5.3K citations

    27

    h-index

  5. PB
    Paul Bamborough

    GlaxoSmithKline (United Kingdom), United Kingdom

    30 publications · 3.3K citations

    26

    h-index

1–5 of 7.6K

Institutions

1.5K

  1. University of Oxford

    Oxford, United Kingdom

    52 h-index

    520 publications

    110.3K citations

  2. Harvard University

    Cambridge, United States

    50 h-index

    378 publications

    117.4K citations

  3. Dana-Farber Cancer Institute

    Boston, United States

    42 h-index

    414 publications

    142.3K citations

  4. National Institutes of Health

    Bethesda, United States

    32 h-index

    121 publications

    28.4K citations

  5. GlaxoSmithKline (United Kingdom)

    London, United Kingdom

    28 h-index

    336 publications

    36.7K citations

  6. Genomics (United Kingdom)

    Oxford, United Kingdom

    26 h-index

    167 publications

    65.4K citations

  7. Goethe University Frankfurt

    Frankfurt am Main, Germany

    23 h-index

    56 publications

    3.6K citations

  8. Genomics England

    London, United Kingdom

    23 h-index

    96 publications

    15.4K citations

1–8 of 1.5K

Venues

  1. Journal of Medicinal Chemistry

    107 publications · 8.8K citations

    53

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  2. Proceedings of the National Academy of Sciences

    PNAS · 37 publications · 6K citations

    33

    h-index

  3. Journal of Biological Chemistry

    JBC · 37 publications · 3.2K citations

    31

    h-index

  4. Molecular and Cellular Biology

    MCB · 22 publications · 3.3K citations

    22

    h-index

  5. Molecular Cell

    20 publications · 6.5K citations

    20

    h-index

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