Concepedia

Synthesis, biological evaluation, and modeling studies of inhibitors aimed at the malarial proteases plasmepsins I and II

Daniel Muthas, Daniel Nöteberg, Yogesh Sabnis, Elizabeth Hamelink, Lotta Vrang, Bertil Samuelsson, Anders Karlén, Anders Hallberg

Bioorganic & Medicinal Chemistry · 2005 · 40 citations · 33 references

DOI

Concepts

References

33

The Protein Data Bank

Helen M. Berman · Nucleic Acids Research · 2000 · 39.8K citations

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Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

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Genome sequence of the human malaria parasite Plasmodium falciparum

Malcolm J. Gardner, Neil Hall, Eula Fung et al. · Nature · 2002 · 4.5K citations · Full text

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Comparative molecular field analysis (CoMFA). 1. Effect of shape on binding of steroids to carrier proteins

Richard D. Cramer, David E. Patterson, Jeffrey D. Bunce · Journal of the American Chemical Society · 1988 · 3.9K citations

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Macromodel—an integrated software system for modeling organic and bioorganic molecules using molecular mechanics

F. MOHAMADI, Nigel G. J. Richards, Wayne C. Guida et al. · Journal of Computational Chemistry · 1990 · 3.8K citations

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