p53 suppresses carcinoma progression by inhibiting mTOR pathway activation

Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer

Arkaitz Carracedo, Li Ma, Julie Teruya‐Feldstein et al. · Journal of Clinical Investigation · 2008 · 1.4K citations · Full text

Induction of medulloblastomas in<i>p53</i>-null mutant mice by somatic inactivation of<i>Rb</i>in the external granular layer cells of the cerebellum

Silvia Marino, Marc Vooijs, Hanneke van der Gulden et al. · Genes & Development · 2000 · 890 citations · Full text

Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model

Ralph Meuwissen, Sabine C. Linn, R. Ilona Linnoila et al. · Cancer Cell · 2003 · 638 citations · Full text

Oncogenic Agent, Medicine, Conditional Mouse Model +12

Inactivation of the p53 pathway in retinoblastoma

Nikia A. Laurie, Stacy L. Donovan, Chie-Schin Shih et al. · Nature · 2006 · 585 citations

Cell Regulation, Cell Proliferation, Tumor Suppressor +5

Early restriction of peripheral and proximal cell lineages during formation of the lung

Anne‐Karina T. Perl, Susan E. Wert, András Nagy et al. · Proceedings of the National Academy of Sciences · 2002 · 527 citations · Full text

Inflammatory Lung Disease, Lung Inflammation, Genetics +21