Nagako Akeno

Osteoblast-specific Knockout of the Insulin-like Growth Factor (IGF) Receptor Gene Reveals an Essential Role of IGF Signaling in Bone Matrix Mineralization

Mei Zhang, Shouhong Xuan, Mary Bouxsein et al. · Journal of Biological Chemistry · 2002 · 701 citations · Full text

Medicine, Developmental Biology, Endocrinology +17

Hypoxia induces chondrocyte-specific gene expression in mesenchymal cells in association with transcriptional activation of Sox9

Jared C. Robins, Nagako Akeno, Aditi Mukherjee et al. · Bone · 2005 · 311 citations

Life Sciences, Cell Biology, Molecular Biology +16

Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity

Joel D. Pearson, Katherine Huang, Marek Pacal et al. · Cancer Cell · 2021 · 175 citations · Full text

Medicine, Cancer Biology, Oncology +9

Endogenous expression of Hras ^G12V induces developmental defects and neoplasms with copy number imbalances of the oncogene

Xu Chen, Norisato Mitsutake, Krista LaPerle et al. · Proceedings of the National Academy of Sciences · 2009 · 140 citations · Full text

Medicine, Genetics, Oncology +17

Induction of Vascular Endothelial Growth Factor by IGF-I in Osteoblast-Like Cells Is Mediated by the PI3K Signaling Pathway through the Hypoxia-Inducible Factor-2α

Nagako Akeno, Jared C. Robins, Mei Zhang et al. · Endocrinology · 2002 · 132 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16