Concepedia

Immunomodulatory drugs lenalidomide and pomalidomide inhibit multiple myeloma-induced osteoclast formation and the RANKL/OPG ratio in the myeloma microenvironment targeting the expression of adhesion molecules

Marina Bolzoni, Paola Storti, Sabrina Bonomini, Katia Todoerti, Daniela Guasco, Denise Toscani, Luca Agnelli, Antonino Neri, Vittorio Rizzoli, Nicola Giuliani

Experimental Hematology · 2012 · 76 citations · 33 references

DOIFull text

Open access

Concepts

References

33

Thalidomide and immunomodulatory derivatives augment natural killer cell cytotoxicity in multiple myeloma

Faith E. Davies, Noopur Raje, Teru Hideshima et al. · Blood · 2001 · 905 citations

, , +12

Thalidomide and its analogs overcome drug resistance of human multiple myeloma cells to conventional therapy

Teru Hideshima, Dharminder Chauhan, Yoshihito Shima et al. · Blood · 2000 · 859 citations

, , +16

Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha.

Laura G. Corral, Patrick Haslett, George W. Muller et al. · PubMed · 1999 · 731 citations

, , +17

Apoptotic signaling induced by immunomodulatory thalidomide analogs in human multiple myeloma cells: therapeutic implications

Nicholas Mitsiades, Constantine S. Mitsiades, Vassiliki Poulaki et al. · Blood · 2002 · 667 citations · Full text

, , +17

Differential Cytokine Modulation and T Cell Activation by Two Distinct Classes of Thalidomide Analogues That Are Potent Inhibitors of TNF-α

Laura G. Corral, Patrick Haslett, George W. Muller et al. · The Journal of Immunology · 1999 · 654 citations · Full text

, , +16