Constantine S. Mitsiades

BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc

Jake Delmore, Ghayas C. Issa, Madeleine E. Lemieux et al. · Cell · 2011 · 2.8K citations · Full text

Medicine, Immunology, Therapeutic Efficacy +7

The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins

Gang Lu, Richard E. Middleton, Huahang Sun et al. · Science · 2013 · 1.5K citations · Full text

Hematological Malignancy, Cereblon-dependent Destruction, Developmental Biology +15

NF-κB as a Therapeutic Target in Multiple Myeloma

Teru Hideshima, Dharminder Chauhan, Paul G. Richardson et al. · Journal of Biological Chemistry · 2002 · 891 citations · Full text

Targeting transcription regulation in cancer with a covalent CDK7 inhibitor

Nicholas Kwiatkowski, Tinghu Zhang, Peter B. Rahl et al. · Nature · 2014 · 882 citations · Full text

Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma

Paul G. Richardson, Edie Weller, Sagar Lonial et al. · Blood · 2010 · 855 citations · Full text