Rescue of Hippo coactivator YAP1 triggers DNA damage–induced apoptosis in hematological cancers

Francesca Cottini, Teru Hideshima, Chunxiao Xu, +18

Nature Medicine

Drugging the lncRNA MALAT1 via LNA gapmeR ASO inhibits gene expression of proteasome subunits and triggers anti-multiple myeloma activity

Nicola Amodio, Maria Angelica Stamato, Giada Juli, +15

Leukemia

Identification of microRNA expression patterns and definition of a microRNA/mRNA regulatory network in distinct molecular groups of multiple myeloma

Marta Lionetti, M. Biasiolo, Luca Agnelli, +8

Blood

Dependence on glutamine uptake and glutamine addiction characterize myeloma cells: a new attractive target

Marina Bolzoni, Martina Chiu, Fabrizio Accardi, +22

Blood

Functional validation of the anaplastic lymphoma kinase signature identifies CEBPB and Bcl2A1 as critical target genes

Roberto Piva, Elisa Pellegrino, Michela Mattioli, +10

Journal of Clinical Investigation

Cancer ResearchLymphoid NeoplasiaSignaling PathwayFunctional ValidationReceptor Tyrosine Kinase +12

Gene Expression Profiling Uncovers Molecular Classifiers for the Recognition of Anaplastic Large-Cell Lymphoma Within Peripheral T-Cell Neoplasms

Roberto Piva, Luca Agnelli, Elisa Pellegrino, +17

Journal of Clinical Oncology

A SNP microarray and FISH‐based procedure to detect allelic imbalances in multiple myeloma: An integrated genomics approach reveals a wide gene dosage effect

Luca Agnelli, Laura Mosca, Sonia Fabris, +8

Genes Chromosomes and Cancer

Increased osteocyte death in multiple myeloma patients: role in myeloma-induced osteoclast formation

Nicola Giuliani, Marzia Ferretti, Marina Bolzoni, +9

Leukemia

Hematological MalignancyBone Marrow FailureMedicineApoptosisImmunology +9

Gene expression profiling of plasma cell dyscrasias reveals molecular patterns associated with distinct IGH translocations in multiple myeloma

Michela Mattioli, Luca Agnelli, Sonia Fabris, +13

Oncogene

Hematological MalignancyDistinct Igh TranslocationsMedicineMalignant Blood DisorderHematology +8

Revealing the Impact of Structural Variants in Multiple Myeloma

Even H. Rustad, Venkata Yellapantula, Dominik Głodzik, +24

Blood Cancer Discovery