Dependence on glutamine uptake and glutamine addiction characterize myeloma cells: a new attractive target

Marina Bolzoni, Martina Chiu, Fabrizio Accardi, +22

Blood

ILF2 Is a Regulator of RNA Splicing and DNA Damage Response in 1q21-Amplified Multiple Myeloma

Matteo Marchesini, Yamini Ogoti, Elena Fiorini, +26

Cancer Cell

Hematological MalignancyTranscriptional RegulationImmunologyRna SplicingPathology +5

Increased osteocyte death in multiple myeloma patients: role in myeloma-induced osteoclast formation

Nicola Giuliani, Marzia Ferretti, Marina Bolzoni, +9

Leukemia

Hematological MalignancyBone Marrow FailureMedicineApoptosisImmunology +9

Hypoxia-inducible factor (HIF)-1α suppression in myeloma cells blocks tumoral growth in vivo inhibiting angiogenesis and bone destruction

Paola Storti, Marina Bolzoni, Gaetano Donofrío, +17

Leukemia

Tumor BiologyHypoxia-inducible FactorTumoral GrowthMedicineHypoxia (Medicine) +9

Angiogenesis and Multiple Myeloma

Nicola Giuliani, Paola Storti, Marina Bolzoni, +2

Cancer Microenvironment

AngiogenesisHematologyPathologyMyelopoiesisMultiple Myeloma +3

Telomere Dysfunction Drives Aberrant Hematopoietic Differentiation and Myelodysplastic Syndrome

Simona Colla, Derrick Sek Tong Ong, Yamini Ogoti, +39

Cancer Cell

Myelodysplastic SyndromeBone Marrow FailureGeneticsHematologyMedicine +4

Interleukin-27 Acts as Multifunctional Antitumor Agent in Multiple Myeloma

Claudia Cocco, Nicola Giuliani, Emma Di Carlo, +7

Clinical Cancer Research

Myeloma cells inhibit non-canonical wnt co-receptor ror2 expression in human bone marrow osteoprogenitor cells: effect of wnt5a/ror2 pathway activation on the osteogenic differentiation impairment induced by myeloma cells

Marina Bolzoni, Gaetano Donofrío, Paola Storti, +14

Leukemia

Bone Morphogenic ProteinCell SignalingMyeloma CellsCell BiologyMedicine +6

Immunomodulatory drugs lenalidomide and pomalidomide inhibit multiple myeloma-induced osteoclast formation and the RANKL/OPG ratio in the myeloma microenvironment targeting the expression of adhesion molecules

Marina Bolzoni, Paola Storti, Sabrina Bonomini, +7

Experimental Hematology

InflammationHematological MalignancyMedicineCell AdhesionImmunology +6

CC-Chemokine Ligand 20/Macrophage Inflammatory Protein-3α and CC-Chemokine Receptor 6 Are Overexpressed in Myeloma Microenvironment Related to Osteolytic Bone Lesions

Nicola Giuliani, Gina Lisignoli, Simona Colla, +8

Cancer Research