An Outbreak of Histamine Poisoning after Ingestion of the Ground Saury Paste in Eight Patients Taking Isoniazid in Tuberculous Ward

Abstract

We concluded that this accident was the histamine fish poisoning. We speculated that those allergy-like symptoms were due to both the increased histamine in the food made with the saury under poor storage conditions and the patients' reduced histaminase activities due to INH. We should perceive possible adverse effects depending on the interactions between certain drugs and food.