Nutrient-Dependent Expression of Insulin-like Peptides from Neuroendocrine Cells in the CNS Contributes to Growth Regulation in Drosophila

Insulin signalling and the regulation of glucose and lipid metabolism

Alan R. Saltiel, C. Ronald Kahn · Nature · 2001 · 5.3K citations · Full text

Life Sciences, Biochemistry, Endocrinology +14

Role of Brain Insulin Receptor in Control of Body Weight and Reproduction

Jens C. Brüning, Dinesh Gautam, Deborah J. Burks et al. · Science · 2000 · 2.2K citations

Life Sciences, Neuroscience, Physiology +17

Disruption of IRS-2 causes type 2 diabetes in mice

Dominic J. Withers, Julio Sanchez Gutierrez, Heather Towery et al. · Nature · 1998 · 1.8K citations

Life Sciences, Endocrinology, Molecular Biology +12

A Mutant <i>Drosophila</i> Insulin Receptor Homolog That Extends Life-Span and Impairs Neuroendocrine Function

Marc Tatar, A. H. Kopelman, Diane Epstein et al. · Science · 2001 · 1.6K citations

Life Sciences, Biology, Genetics +17

An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control

Walter Brogiolo, Hugo Stocker, Tomoatsu Ikeya et al. · Current Biology · 2001 · 1.3K citations · Full text

Life Sciences, Biology, Endocrinology +15