Ernst Hafen

Extension of Life-Span by Loss of CHICO, a <i>Drosophila</i> Insulin Receptor Substrate Protein

David J. Clancy, David Gems, Lawrence G. Harshman et al. · Science · 2001 · 1.4K citations

Education, Biology, Genetics +17

Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex

James Brugarolas, Kui Lei, Rebecca L. Hurley et al. · Genes & Development · 2004 · 1.4K citations · Full text

Medicine, Cell Biology, Oncology +17

An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control

Walter Brogiolo, Hugo Stocker, Tomoatsu Ikeya et al. · Current Biology · 2001 · 1.3K citations · Full text

Life Sciences, Biology, Endocrinology +15

A conserved DNA sequence in homoeotic genes of the Drosophila Antennapedia and bithorax complexes

William McGinnis, Michael Levine, Ernst Hafen et al. · Nature · 1984 · 1.1K citations

Life Sciences, Genetics, Molecular Genetics +10

Insulin Activation of Rheb, a Mediator of mTOR/S6K/4E-BP Signaling, Is Inhibited by TSC1 and 2

Attila Garami, Fried Zwartkruis, Takahiro Nobukuni et al. · Molecular Cell · 2003 · 1K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13