Concepedia

Critical role for apoptosis signal-regulating kinase 1 in the development of inflammatory K/BxN serum-induced arthritis

Stephen J. Mnich, Patrick M. Blanner, Liangbiao George Hu, Alexander F. Shaffer, Fernando A. Happa, Shawn P. O’Neil, Okechukwu Ukairo, Dave Weiss, Eric A. Welsh, Chad Storer,

International Immunopharmacology · 2010 · 36 citations · 32 references

DOI

Concepts

References

32

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

John C. Lee, Jeffrey T. Laydon, Peter McDonnell et al. · Nature · 1994 · 3.3K citations

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Mammalian thioredoxin is a direct inhibitor of apoptosis signal‐regulating kinase (ASK) 1

Masao Saitoh · The EMBO Journal · 1998 · 2.4K citations · Full text

, , +13

Induction of Apoptosis by ASK1, a Mammalian MAPKKK That Activates SAPK/JNK and p38 Signaling Pathways

Hidenori Ichijo, Eisuke Nishida, Kenji Irie et al. · Science · 1997 · 2.3K citations

, , +16

ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis

Kei Tobiume, Atsushi Matsuzawa, Takumi Takahashi et al. · EMBO Reports · 2001 · 1.2K citations · Full text

, , +13

c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis

Zuoning Han, David L. Boyle, Lufen Chang et al. · Journal of Clinical Investigation · 2001 · 775 citations · Full text

, , +13