Benzoxaborole antimalarial agents. Part 2: Discovery of fluoro-substituted 7-(2-carboxyethyl)-1,3-dihydro-1-hydroxy-2,1-benzoxaboroles

Spiroindolones, a Potent Compound Class for the Treatment of Malaria

Matthias Rottmann, Case W. McNamara, Bryan K. S. Yeung et al. · Science · 2010 · 1.2K citations · Full text

Medicine, Pharmacokinetics, Pharmacology +16

An Antifungal Agent Inhibits an Aminoacyl-tRNA Synthetase by Trapping tRNA in the Editing Site

Fernando Rock, Weimin Mao, A. Yaremchuk et al. · Science · 2007 · 631 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +17

Discovery of a New Boron-Containing Antifungal Agent, 5-Fluoro-1,3-dihydro-1-hydroxy-2,1- benzoxaborole (AN2690), for the Potential Treatment of Onychomycosis

Stephen J. Baker, Yong-Kang Zhang, Tsutomu Akama et al. · Journal of Medicinal Chemistry · 2006 · 310 citations

Pharmacy, Dermatology, Medicinal Chemistry +17

Discovery and structure–activity study of a novel benzoxaborole anti-inflammatory agent (AN2728) for the potential topical treatment of psoriasis and atopic dermatitis

Tsutomu Akama, Stephen J. Baker, Yongkang Zhang et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 210 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Malaria's Drug Miracle in Danger

Martin Enserink · Science · 2010 · 116 citations

Veterinary Medicine, Infectious Diseases, Pharmacology +5