Jacob J. Plattner

An Antifungal Agent Inhibits an Aminoacyl-tRNA Synthetase by Trapping tRNA in the Editing Site

Fernando Rock, Weimin Mao, A. Yaremchuk et al. · Science · 2007 · 631 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +17

Design, Activity, and 2.8 Å Crystal Structure of a <i>C</i> ₂ Symmetric Inhibitor Complexed to HIV-1 Protease

John W. Erickson, David J. Neidhart, John H. VanDrie et al. · Science · 1990 · 528 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +17

ABT-378, a Highly Potent Inhibitor of the Human Immunodeficiency Virus Protease

Hing L. Sham, Dale J. Kempf, Akhteruzammen Molla et al. · Antimicrobial Agents and Chemotherapy · 1998 · 470 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +16

Discovery of a New Boron-Containing Antifungal Agent, 5-Fluoro-1,3-dihydro-1-hydroxy-2,1- benzoxaborole (AN2690), for the Potential Treatment of Onychomycosis

Stephen J. Baker, Yong-Kang Zhang, Tsutomu Akama et al. · Journal of Medicinal Chemistry · 2006 · 310 citations

Pharmacy, Dermatology, Medicinal Chemistry +17

SCYX-7158, an Orally-Active Benzoxaborole for the Treatment of Stage 2 Human African Trypanosomiasis

Robert T. Jacobs, Bakela Nare, Stephen A. Wring et al. · PLoS neglected tropical diseases · 2011 · 299 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14