Robert T. Jacobs

Modulation of Notch Processing by γ-Secretase Inhibitors Causes Intestinal Goblet Cell Metaplasia and Induction of Genes Known to Specify Gut Secretory Lineage Differentiation

Joseph Milano, Jenny McKay, Claude Dagenais et al. · Toxicological Sciences · 2004 · 565 citations

Medicine, Medicinal Chemistry, Pharmacology +15

SCYX-7158, an Orally-Active Benzoxaborole for the Treatment of Stage 2 Human African Trypanosomiasis

Robert T. Jacobs, Bakela Nare, Stephen A. Wring et al. · PLoS neglected tropical diseases · 2011 · 299 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Application of a resazurin-based high-throughput screening assay for the identification and progression of new treatments for human African trypanosomiasis

Tana Bowling, Luke Mercer, Robert Don et al. · International Journal for Parasitology Drugs and Drug Resistance · 2012 · 107 citations · Full text

Veterinary Medicine, Infectious Diseases, Medicinal Chemistry +14

Discovery of Novel Benzoxaborole-Based Potent Antitrypanosomal Agents

Dazhong Ding, Yaxue Zhao, Qingqing Meng et al. · ACS Medicinal Chemistry Letters · 2010 · 102 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

Discovery of Novel Orally Bioavailable Oxaborole 6-Carboxamides That Demonstrate Cure in a Murine Model of Late-Stage Central Nervous System African Trypanosomiasis

Bakela Nare, Stephen A. Wring, Cyrus J. Bacchi et al. · Antimicrobial Agents and Chemotherapy · 2010 · 102 citations · Full text

Veterinary Medicine, Infectious Diseases, Pharmacology +14