Luke Mercer

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

Wesley C. Van Voorhis, John H. Adams, Roberto Adelfio et al. · PLoS Pathogens · 2016 · 441 citations · Full text

Drug Target, Bioorganic Chemistry, Antiparasitic Agent +17

SCYX-7158, an Orally-Active Benzoxaborole for the Treatment of Stage 2 Human African Trypanosomiasis

Robert T. Jacobs, Bakela Nare, Stephen A. Wring et al. · PLoS neglected tropical diseases · 2011 · 294 citations · Full text

Application of a resazurin-based high-throughput screening assay for the identification and progression of new treatments for human African trypanosomiasis

Tana Bowling, Luke Mercer, Robert Don et al. · International Journal for Parasitology Drugs and Drug Resistance · 2012 · 103 citations · Full text

Antiparasitic Agent, Malaria, Immunology +24

Discovery of Novel Orally Bioavailable Oxaborole 6-Carboxamides That Demonstrate Cure in a Murine Model of Late-Stage Central Nervous System African Trypanosomiasis

Bakela Nare, Stephen A. Wring, Cyrus J. Bacchi et al. · Antimicrobial Agents and Chemotherapy · 2010 · 102 citations · Full text

Identification of a 4-fluorobenzyl l-valinate amide benzoxaborole (AN11736) as a potential development candidate for the treatment of Animal African Trypanosomiasis (AAT)

Tsutomu Akama, Yong-Kang Zhang, Yvonne R. Freund et al. · Bioorganic & Medicinal Chemistry Letters · 2017 · 45 citations · Full text