David Waterson

Antimalarial efficacy of MMV390048, an inhibitor of <i>Plasmodium</i> phosphatidylinositol 4-kinase

Tanya Paquet, Claire Le Manach, Diego González Cabrera et al. · Science Translational Medicine · 2017 · 262 citations · Full text

Crystal Structure of Human MMP9 in Complex with a Reverse Hydroxamate Inhibitor

Siân Rowsell, Paul Hawtin, Claire A. Minshull et al. · Journal of Molecular Biology · 2002 · 255 citations

Crystal Structure, Human Mmp9, Medicine +9

(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of <i>Plasmodium</i>

Marı́a Belén Jiménez-Dı́az, Daniel Ebert, Yandira G. Salinas et al. · Proceedings of the National Academy of Sciences · 2014 · 238 citations · Full text

Phenotypic Screening, Antiparasitic Agent, Malaria +17

UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria

Christel Brunschwig, Nina Lawrence, Dale Taylor et al. · Antimicrobial Agents and Chemotherapy · 2018 · 136 citations · Full text

3,5-Diaryl-2-aminopyridines as a Novel Class of Orally Active Antimalarials Demonstrating Single Dose Cure in Mice and Clinical Candidate Potential

Yassir Younis, Frédèric Douelle, Tzu‐Shean Feng et al. · Journal of Medicinal Chemistry · 2012 · 134 citations · Full text