Eric E. Easom

Discovery of a Potent and Specific <i>M. tuberculosis</i> Leucyl-tRNA Synthetase Inhibitor: (<i>S</i>)-3-(Aminomethyl)-4-chloro-7-(2-hydroxyethoxy)benzo[<i>c</i>][1,2]oxaborol-1(3<i>H</i>)-ol (GSK656)

Xianfeng Li, Vincent Hernandez, Fernando Rock et al. · Journal of Medicinal Chemistry · 2017 · 157 citations · Full text

Discovery of Novel Oral Protein Synthesis Inhibitors of Mycobacterium tuberculosis That Target Leucyl-tRNA Synthetase

Andrés Palencia, Xianfeng Li, Wei Bu et al. · Antimicrobial Agents and Chemotherapy · 2016 · 116 citations · Full text

Drug Target, Molecular Biology, Antimicrobial Chemotherapy +18

Synthesis and structure–activity relationships of novel benzoxaboroles as a new class of antimalarial agents

Yong-Kang Zhang, Jacob J. Plattner, Yvonne R. Freund et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 79 citations

Novel Benzoxaboroles, Antiparasitic Agent, Medicine +6

Targeting <i>Toxoplasma gondii</i> <scp>CPSF</scp> 3 as a new approach to control toxoplasmosis

Andrés Palencia, Alexandre Bougdour, Marie‐Pierre Brenier‐Pinchart et al. · EMBO Molecular Medicine · 2017 · 77 citations · Full text

Discovery of an orally active benzoxaborole prodrug effective in the treatment of Chagas disease in non-human primates

Ángel M. Padilla, Wei Wang, Tsutomu Akama et al. · Nature Microbiology · 2022 · 64 citations · Full text