Eric E. Easom

Discovery of a Potent and Specific <i>M. tuberculosis</i> Leucyl-tRNA Synthetase Inhibitor: (<i>S</i>)-3-(Aminomethyl)-4-chloro-7-(2-hydroxyethoxy)benzo[<i>c</i>][1,2]oxaborol-1(3<i>H</i>)-ol (GSK656)

Xianfeng Li, Vincent Hernandez, Fernando Rock et al. · Journal of Medicinal Chemistry · 2017 · 162 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Discovery of Novel Oral Protein Synthesis Inhibitors of Mycobacterium tuberculosis That Target Leucyl-tRNA Synthetase

Andrés Palencia, Xianfeng Li, Wei Bu et al. · Antimicrobial Agents and Chemotherapy · 2016 · 121 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Synthesis and structure–activity relationships of novel benzoxaboroles as a new class of antimalarial agents

Yong-Kang Zhang, Jacob J. Plattner, Yvonne R. Freund et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 80 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Targeting Toxoplasma gondii CPSF3 as a new approach to control toxoplasmosis

Andrés Palencia, Alexandre Bougdour, Marie‐Pierre Brenier‐Pinchart et al. · EMBO Molecular Medicine · 2017 · 78 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +16

Discovery of an orally active benzoxaborole prodrug effective in the treatment of Chagas disease in non-human primates

Ángel M. Padilla, Wei Wang, Tsutomu Akama et al. · Nature Microbiology · 2022 · 71 citations · Full text

Veterinary Medicine, Infectious Diseases, Pharmacology +16