Concepedia

Role for p27 <sup>Kip1</sup> in Vascular Smooth Muscle Cell Migration

Ji Sun, Steven O. Marx, Hongjun Chen, Michael Poon, Andrew R. Marks, LeRoy E. Rabbani

Circulation · 2001 · 177 citations · 24 references

DOIFull text

Open access

Abstract

Lack of p27(Kip1) reduces rapamycin-mediated inhibition of SMC migration. These novel findings suggest a role for p27(Kip1) in the signaling pathway(s) that regulates SMC migration.

References

24

A mammalian protein targeted by G1-arresting rapamycin–receptor complex

Eric J. Brown, Mark W. Albers, Tae Bum Shin et al. · Nature · 1994 · 2K citations

, , +8

RAFT1: A mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs

David M. Sabatini, Hediye Erdjument‐Bromage, Mary Lui et al. · Cell · 1994 · 1.5K citations

, , +9

Enhanced Growth of Mice Lacking the Cyclin-Dependent Kinase Inhibitor Function of p27

Hiroaki Kiyokawa, Rhonda D. Kineman, Katia Manova‐Todorova et al. · Cell · 1996 · 1.3K citations · Full text

Phosphorylation of the Translational Repressor PHAS-I by the Mammalian Target of Rapamycin

Gregory J. Brunn, Christine C. Hudson, Aleksandar Sekulić et al. · Science · 1997 · 957 citations

lnterleukin-2-mediated elimination of the p27Kipl cyclin-dependent kinase inhibitor prevented by rapamycin

Jamison L. Nourse, Eduardo Firpo, W. Michael Flanagan et al. · Nature · 1994 · 895 citations

, , +10