A Syndrome of Multiorgan Hyperplasia with Features of Gigantism, Tumorigenesis, and Female Sterility in p27 -Deficient Mice

Matthew L. Fero, Michael J. Rivkin, Michael Tasch, +9

Cell

Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients

Peggy L. Porter, Kathleen E. Malone, Patrick J. Heagerty, +5

Nature Medicine

Breast OncologyCell RegulationMedicineCancer BiologyBreast Cancer +7

lnterleukin-2-mediated elimination of the p27Kipl cyclin-dependent kinase inhibitor prevented by rapamycin

Jamison L. Nourse, Eduardo Firpo, W. Michael Flanagan, +6

Nature

InflammationCytokineAnti-inflammatoryAutoimmune DiseaseCell Regulation +8

The Tumor Suppressor Gene Brca1 Is Required for Embryonic Cellular Proliferation in the Mouse

Razqallah Hakem, José Luís de la Pompa, Christian Sirard, +12

Cell

Tumor BiologyEmbryonic Cellular ProliferationDevelopmental BiologyMedicineCell Proliferation +6

Inactivation of a Cdk2 inhibitor during interleukin 2-induced proliferation of human T lymphocytes.

Eduardo Firpo, Andrew Koff, Michael J. Solomon, +1

Molecular and Cellular Biology

ImmunologyImmune RegulationImmunologic MechanismCell CycleCdk2 Inhibitor +15

A new pathway for mitogen-dependent Cdk2 regulation uncovered in p27Kip1-deficient cells

Steve Coats, Peter Whyte, Matthew L. Fero, +5

Current Biology

Signal TransductionCell RegulationMolecular PathwaySignaling PathwayReceptor Tyrosine Kinase +9

A mouse model for cyclin E-dependent genetic instability and tumorigenesis

Keith R. Loeb, Heather Kostner, Eduardo Firpo, +4

Cancer Cell

Knockout MouseGenome InstabilityMedicineCell CycleSystems Biology +4

Functional analysis of pRb2/p130 interaction with cyclins.

Pier Paolo Claudio, Antonio De Luca, Candace M. Howard, +5

PubMed

Molecular BiologyCell CycleFunctional AnalysisChemical BiologyCancer Biology +14

Separation of telomerase functions by reverse genetics

Shibani Mukherjee, Eduardo Firpo, Yang Wang, +1

Proceedings of the National Academy of Sciences

Reverse GeneticsGeneticsApoptosisMolecular BiologyCell Death +16

Inactivation of a Cdk2 Inhibitor during Interleukin 2-Induced Proliferation of Human T Lymphocytes

Eduardo Firpo, Andrew Koff, Mark J. Solomon, +1

Molecular and Cellular Biology

T-regulatory CellImmune RegulationImmunologyImmunologic MechanismCell Cycle +17