Simian immunodeficiency virus lentivector corrects human X-linked chronic granulomatous disease in the NOD/SCID mouse xenograft

In Vivo Gene Delivery and Stable Transduction of Nondividing Cells by a Lentiviral Vector

Luigi Naldini, Ulrike Blömer, Philippe Gallay et al. · Science · 1996 · 4.9K citations

Pharmacy, Biotechnology, Molecular Medicine +14

Chronic Granulomatous Disease: Report on a National Registry of 368 Patients

Jerry A. Winkelstein, Mary C. Marino, Richard B. Johnston et al. · Medicine · 2000 · 1.7K citations

Medicine, Dermatology, Internal Medicine +5

Transcription Start Regions in the Human Genome Are Favored Targets for MLV Integration

Xiaolin Wu, Yuan Li, Bruce Crise et al. · Science · 2003 · 1.3K citations

Life Sciences, Genetics, Molecular Biology +17

Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1

Marion Ott, Manfred Schmidt, Kerstin Schwarzwaelder et al. · Nature Medicine · 2006 · 1.2K citations

Life Sciences, Immunology, Molecular Medicine +10

Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration

Eugenio Montini, Daniela Cesana, Manfred Schmidt et al. · Nature Biotechnology · 2006 · 705 citations

Medicine, Biotechnology, Oncology +14