Daniela Cesana

Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration

Eugenio Montini, Daniela Cesana, Manfred Schmidt et al. · Nature Biotechnology · 2006 · 705 citations

Medicine, Biotechnology, Oncology +14

The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy

Eugenio Montini, Daniela Cesana, Manfred Schmidt et al. · Journal of Clinical Investigation · 2009 · 573 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +16

Site-specific integration and tailoring of cassette design for sustainable gene transfer

Angelo Lombardo, Daniela Cesana, Pietro Genovese et al. · Nature Methods · 2011 · 336 citations

Life Sciences, Genetics, Molecular Biology +16

Lentiviral vector common integration sites in preclinical models and a clinical trial reflect a benign integration bias and not oncogenic selection

Alessandra Biffi, Cynthia C. Bartolomae, Daniela Cesana et al. · Blood · 2011 · 241 citations · Full text

Life Sciences, Pharmaceutical Biotechnology, Gene Therapy +11

Uncovering and Dissecting the Genotoxicity of Self-inactivating Lentiviral Vectors In Vivo

Daniela Cesana, Marco Ranzani, Monica Volpin et al. · Molecular Therapy · 2014 · 187 citations · Full text

Medicine, Cancer Biology, Oncology +15