Daniela Cesana

Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration

Eugenio Montini, Daniela Cesana, Manfred Schmidt et al. · Nature Biotechnology · 2006 · 705 citations

Cell Therapy, Medicine, Stem Cell Toxicology +8

The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy

Eugenio Montini, Daniela Cesana, Manfred Schmidt et al. · Journal of Clinical Investigation · 2009 · 571 citations · Full text

Site-specific integration and tailoring of cassette design for sustainable gene transfer

Angelo Lombardo, Daniela Cesana, Pietro Genovese et al. · Nature Methods · 2011 · 332 citations

Sustainable Gene Transfer, Engineering, Genetics +13

Lentiviral vector common integration sites in preclinical models and a clinical trial reflect a benign integration bias and not oncogenic selection

Alessandra Biffi, Cynthia C. Bartolomae, Daniela Cesana et al. · Blood · 2011 · 238 citations · Full text

Comprehensive genomic access to vector integration in clinical gene therapy

Richard Gabriel, Ralph Eckenberg, Anna Paruzynski et al. · Nature Medicine · 2009 · 186 citations

Bioinformatics, Medical Treatment, Engineering +10