Concepedia

Notch induces human T-cell receptor γδ+ thymocytes to differentiate along a parallel, highly proliferative and bipotent CD4 CD8 double-positive pathway

Stefanie Van Coppernolle, Stijn Vanhee, Greet Verstichel, Sylvia Snauwaert, Ashley van der Spek, Imke Velghe, Mieke Sinnesael, Mirjam H.M. Heemskerk, Tom Taghon, Georges Leclercq,

Leukemia · 2011 · 30 citations · 37 references

DOI

Concepts

References

37

Activating Mutations of <i>NOTCH1</i> in Human T Cell Acute Lymphoblastic Leukemia

Andrew P. Weng, Adolfo A. Ferrando, Woojoong Lee et al. · Science · 2004 · 2.7K citations

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<i>FBW7</i> mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors

Jennifer O’Neil, Jonathan Grim, Peter R. Strack et al. · The Journal of Experimental Medicine · 2007 · 662 citations · Full text

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Thymic Origin of Intestinal αß T Cells Revealed by Fate Mapping of RORγt <sup>+</sup> Cells

Gérard Eberl, Dan R. Littman · Science · 2004 · 518 citations

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The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia

Benjamin J. Thompson, Silvia Buonamici, Maria Luisa Sulis et al. · The Journal of Experimental Medicine · 2007 · 486 citations · Full text

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Thymic Selection Determines γδ T Cell Effector Fate: Antigen-Naive Cells Make Interleukin-17 and Antigen-Experienced Cells Make Interferon γ

Kirk D.C. Jensen, Xiaoqin Su, Sunny Shin et al. · Immunity · 2008 · 470 citations · Full text

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