A cell atlas of human thymic development defines T cell repertoire formation

Jong-Eun Park, Rachel A. Botting, Cecilia Domínguez Conde, +39

Science

Stellate Cells, Hepatocytes, and Endothelial Cells Imprint the Kupffer Cell Identity on Monocytes Colonizing the Liver Macrophage Niche

Johnny Bonnardel, Wouter T’Jonck, Djoere Gaublomme, +19

Immunity

A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia

Apostolos Klinakis, Camille Lobry, Omar Abdel‐Wahab, +16

Nature

Hematological MalignancyTumor BiologyHematologyMyeloid NeoplasiaMyelopoiesis +8

PHF6 mutations in T-cell acute lymphoblastic leukemia

Pieter Van Vlierberghe, Teresa Palomero, Hossein Khiabanian, +30

Nature Genetics

Hematological MalignancyPhf6 MutationsMixed-phenotype Acute LeukemiaHematologyAdult T-cell Leukemia-lymphoma +1

Developmental and Molecular Characterization of Emerging β- and γδ-Selected Pre-T Cells in the Adult Mouse Thymus

Tom Taghon, Mary A. Yui, Rashmi Pant, +2

Immunity

Thymus BiologyMolecular CharacterizationDevelopmental BiologyLymphocyte DevelopmentImmune Cell Development +12

ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia

Sofie Peirs, Filip Matthijssens, Steven Goossens, +18

Blood

A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL)

Konstantinos J. Mavrakis, Joni Van der Meulen, Andrew L. Wolfe, +14

Nature Genetics

ImmunologyMicrorna DetectionSmall RnaAdult T-cell Leukemia-lymphomaImmunotherapy +4

Quantification of Reverse Transcriptase Activity by Real-Time PCR as a Fast and Accurate Method for Titration of HIV, Lenti- and Retroviral Vectors

Jolien Vermeíre, Evelien Naessens, Hanne Vanderstraeten, +6

PLoS ONE

Viral ReplicationViral DiagnosticsImmunologyPathologyNucleic Acid Amplification Test +17

Generation of T Cells from Human Embryonic Stem Cell-Derived Hematopoietic Zones

Frank Timmermans, Imke Velghe, Lieve Vanwalleghem, +9

The Journal of Immunology

Cell TherapyLymphocyte DevelopmentImmunologyCell DifferentiationT Cells +18

The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia

Joni Van der Meulen, Viraj R. Sanghvi, Konstantinos J. Mavrakis, +20

Blood