Gain-of-Function Pyrin Mutations Induce NLRP3 Protein-Independent Interleukin-1β Activation and Severe Autoinflammation in Mice

Cryopyrin activates the inflammasome in response to toxins and ATP

Sanjeev Mariathasan, David S. Weiss, Kim Newton et al. · Nature · 2006 · 3K citations

Life Sciences, Cell Biology, Molecular Biology +7

A candidate gene for familial Mediterranean fever

Alain Bernot, Christian Clépet, Corinne Da Silva et al. · Nature Genetics · 1997 · 1.5K citations

Life Sciences, Genetics, Molecular Genetics +7

Ancient Missense Mutations in a New Member of the RoRet Gene Family Are Likely to Cause Familial Mediterranean Fever

The International FMF Consortium · Cell · 1997 · 1.5K citations · Full text

Life Sciences, Genetics, Molecular Genetics +10

Familial Mediterranean fever

E Sohar, J Gafni, Harry Heller · The American Journal of Medicine · 1967 · 1.1K citations

Familial Mediterranean Fever

Servet Akar, Feride Yüksel, Mehmet Tunca et al. · Medicine · 2012 · 1K citations

Social Sciences, Clinical Sciences, Internal Medicine +17