Jun Cheng

A Critical Role for IL-21 in Regulating Immunoglobulin Production

Katsutoshi Ozaki, Rosanne Spolski, Carl G. Feng et al. · Science · 2002 · 956 citations

Primary Immunodeficiency, Inflammation, Regulating Immunoglobulin Production +14

Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection

Chen Yao, Hong‐Wei Sun, Neal E. Lacey et al. · Nature Immunology · 2019 · 543 citations

Autoimmune Disease, Key Regulator, Single Cell Sequencing +11

Gain-of-Function Pyrin Mutations Induce NLRP3 Protein-Independent Interleukin-1β Activation and Severe Autoinflammation in Mice

Jae Jin Chae, Young-Hun Cho, Geun‐Shik Lee et al. · Immunity · 2011 · 446 citations · Full text

Inflammation, Cytokine, Signal Transduction +10

Upregulation of miRNA-155 promotes tumour angiogenesis by targeting VHL and is associated with poor prognosis and triple-negative breast cancer

Weicheng Kong, Lili He, Eric J. Richards et al. · Oncogene · 2013 · 422 citations · Full text

Breast Oncology, Medicine, Pathology +11

Targeted Disruption of Pyrin, the FMF Protein, Causes Heightened Sensitivity to Endotoxin and a Defect in Macrophage Apoptosis

Jae Jin Chae, Hirsh D. Komarow, Jun Cheng et al. · Molecular Cell · 2003 · 407 citations · Full text

Inflammation, Mitophagy, Signal Transduction +14