Concepedia

Cyclic disulfides as functional mimics of the histone deacetylase inhibitor FK-228

Jared R. Mays, José A. Restituyo, Rebeccah J. Katzenberger, David A. Wassarman, Scott R. Rajski

Tetrahedron Letters · 2007 · 12 citations · 23 references

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References

23

Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

Michael S. Finnin, Jill R. Donigian, Alona Cohen et al. · Nature · 1999 · 1.7K citations

, , +12

FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases.

Ryohei Furumai, Akihisa Matsuyama, Nobuyuki Kobashi et al. · PubMed · 2002 · 744 citations

, , +13

Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes

Myoung Sook Kim, Ho Jeong Kwon, You Mie Lee et al. · Nature Medicine · 2001 · 731 citations

, , +14

Suppression of tumor growth through disruption of hypoxia-inducible transcription

Andrew L. Kung, Stream Wang, Jeffery M. Klco et al. · Nature Medicine · 2000 · 499 citations

, , +14

Bioactivation as a Model for Drug Design Bioreductive Alkylation

Harold W. Moore · Science · 1977 · 433 citations

, , +5