Concepedia

Disulfide Bond Engineering

Disulfide Bond Engineering is a protein engineering methodology that involves the strategic introduction or optimization of disulfide bonds within a protein structure to enhance its conformational stability and resistance to thermal denaturation.

398

Publications

20.6K

Citations

1.9K

Authors

627

Institutions

Publications per year

2017–2026

145

Parents

Publications

398

Disulfide Cross-Linked Hyaluronan Hydrogels

Xiao Zheng Shu, Yanchun Liu, Yi Luo et al. · Biomacromolecules · 2002 · 612 citations

, , +17

Disulfide by Design 2.0: a web-based tool for disulfide engineering in proteins

Douglas B. Craig, Alan A. Dombkowski · BMC Bioinformatics · 2013 · 590 citations · Full text

, , +17

Manipulating disulfide bond formation and protein folding in the endoplasmic reticulum.

Ineke Braakman, Jonne Helenius, Ari Helenius · The EMBO Journal · 1992 · 415 citations · Full text

, , +16

Contour Length and Refolding Rate of a Small Protein Controlled by Engineered Disulfide Bonds

Sri Rama Koti Ainavarapu, Jasna Brujić, Hector H. Huang et al. · Biophysical Journal · 2006 · 346 citations · Full text

, , +17

Engineered disulfide bonds as probes of the folding pathway of barnase: Increasing the stability of proteins against the rate of denaturation

Jane Clarke, Alan R. Fersht · Biochemistry · 1993 · 344 citations

, , +17

1–5 of 398

Authors

1.9K

  1. CW
    Chuanliu Wu

    Xiamen University, China

    7 publications · 231 citations

    8

    h-index

  2. LL
    Lei Liu

    Tsinghua University, China

    7 publications · 250 citations

    7

    h-index

  3. YZ
    Yibing Zhao

    Xiamen University, China

    6 publications · 155 citations

    6

    h-index

  4. DJ
    David J. Craik

    The University of Queensland, Australia

    6 publications · 523 citations

    6

    h-index

  5. DB
    Donald Bierer

    Bayer (Germany), Germany

    5 publications · 119 citations

    5

    h-index

1–5 of 1.9K

Institutions

627

  1. Tsinghua University

    Beijing, China

    13 h-index

    35 publications

    1.6K citations

  2. Chinese Academy of Sciences

    Beijing, China

    12 h-index

    39 publications

    1.7K citations

  3. The University of Queensland

    Brisbane, Australia

    10 h-index

    42 publications

    2.6K citations

  4. University of Science and Technology of China

    Hefei, China

    9 h-index

    32 publications

    1.1K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    9 h-index

    50 publications

    1.3K citations

  6. Jiangnan University

    Wuxi, China

    9 h-index

    44 publications

    1.4K citations

  7. Indian Institute of Science Bangalore

    Bengaluru, India

    7 h-index

    26 publications

    1.5K citations

  8. Hefei University of Technology

    Hefei, China

    7 h-index

    27 publications

    639 citations

1–8 of 627

Venues

  1. Journal of Biological Chemistry

    JBC · 19 publications · 1.2K citations

    16

    h-index

  2. Biochemistry

    18 publications · 1.3K citations

    15

    h-index

  3. Chemical Communications

    ChemComm · 13 publications · 569 citations

    12

    h-index

  4. Protein Engineering Design and Selection

    PEDS · 11 publications · 945 citations

    11

    h-index

  5. Tetrahedron

    11 publications · 438 citations

    11

    h-index

1–5