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Synthesis and Antioxidant Activity of Flavanoid Derivatives Containing a 1,4-Benzodioxane Moiety
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Citations
17
References
2000
Year
Bioorganic ChemistryLipid PeroxidationAntioxidant ActivityOrganic ChemistryRedox BiologyPolyphenolicsOxidative StressMedicinal ChemistrySuperoxide AnionPhytochemicalInhibitory ActivityBiochemistryReactive Oxygen SpecieFlavanoid DerivativesPharmacologyNatural Sciences1,4-Benzodioxane MoietyPhytochemistryMedicineHuman Polymorphonuclear Leukocytes
Flavanoids bearing a 1,4-benzodioxane moiety [rac-15a, -16a, -17, -18, (-)-15a, (-)-16a] were prepared from protocatechualdehyde (5) and tested for inhibitory activity on the superoxide anion (O2.-) release by human polymorphonuclear leukocytes (PMNLs).
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