Concepedia

CYP2D6 genotype in relation to tamoxifen efficacy in a Dutch cohort of the tamoxifen exemestane adjuvant multinational (TEAM) trial

Vincent O. Dezentjé, Ron H. N. van Schaik, J. M. Vletter-Bogaartz, Tahar van der Straaten, Judith A.M. Wessels, Elma Meershoek – Klein Kranenbarg, E. Berns, Caroline Seynaeve, Hein Putter, Cornelis J.�H. van de Velde,

Breast Cancer Research and Treatment · 2013 · 48 citations · 33 references

DOI

Concepts

References

33

CYP2D6 Genotype, Antidepressant Use, and Tamoxifen Metabolism During Adjuvant Breast Cancer Treatment

Zeruesenay Desta, Vered Stearns, Brent B. Ward et al. · JNCI Journal of the National Cancer Institute · 2005 · 942 citations · Full text

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Active Tamoxifen Metabolite Plasma Concentrations After Coadministration of Tamoxifen and the Selective Serotonin Reuptake Inhibitor Paroxetine

Vered Stearns · JNCI Journal of the National Cancer Institute · 2003 · 849 citations · Full text

, , +17

Pharmacogenetics of Tamoxifen Biotransformation Is Associated With Clinical Outcomes of Efficacy and Hot Flashes

Matthew P. Goetz, James M. Rae, Vera J. Suman et al. · Journal of Clinical Oncology · 2005 · 786 citations · Full text

, , +16

Comprehensive Evaluation of Tamoxifen Sequential Biotransformation by the Human Cytochrome P450 System in Vitro: Prominent Roles for CYP3A and CYP2D6

Zeruesenay Desta, Bryan A. Ward, Nadia Soukhova et al. · Journal of Pharmacology and Experimental Therapeutics · 2004 · 645 citations

, , +17

Association Between CYP2D6 Polymorphisms and Outcomes Among Women With Early Stage Breast Cancer Treated With Tamoxifen

Werner Schroth · JAMA · 2009 · 529 citations · Full text

, , +17