Concepedia

Cyp2d6 Phenotyping

CYP2D6 Phenotyping is a pharmacogenetic assessment method that classifies individuals based on their metabolic activity of the CYP2D6 enzyme, determined through the measurement of probe drug metabolism or phenotypic markers, to infer functional enzyme status distinct from genotypic prediction alone.

503

Publications

27.4K

Citations

2.7K

Authors

917

Institutions

Publications per year

2017–2026

101

Parents

Publications

503

The CYP2D6 Activity Score: Translating Genotype Information into a Qualitative Measure of Phenotype

Andrea Gaedigk, S.D. Simon, R PEARCE et al. · Clinical Pharmacology & Therapeutics · 2007 · 793 citations

, , +16

Standardizing <i><scp>CYP</scp>2D6</i> Genotype to Phenotype Translation: Consensus Recommendations from the Clinical Pharmacogenetics Implementation Consortium and Dutch Pharmacogenetics Working Group

Kelly E. Caudle, Katrin Sangkuhl, Michelle Whirl‐Carrillo et al. · Clinical and Translational Science · 2019 · 525 citations · Full text

, , +15

Prediction of CYP2D6 phenotype from genotype across world populations

Andrea Gaedigk, Katrin Sangkuhl, Michelle Whirl‐Carrillo et al. · Genetics in Medicine · 2016 · 516 citations · Full text

, , +17

Quantitative effect of CYP2D6 genotype and inhibitors on tamoxifen metabolism: Implication for optimization of breast cancer treatment

Sandra Regina de Oliveira Borges, Zereunesay Desta, L LI et al. · Clinical Pharmacology & Therapeutics · 2006 · 479 citations · Full text

, , +17

Non‐linear pharmacokinetics of MDMA (‘ecstasy’) in humans

Rafael de la Torre, Magı́ Farré, Jordi Ortuño et al. · British Journal of Clinical Pharmacology · 2000 · 407 citations · Full text

, , +14

1–5 of 503

Authors

2.7K

  1. AG
    Andrea Gaedigk

    Children's Mercy Hospital, United States

    32 publications · 4.1K citations

    23

    h-index

  2. JS
    J. Steven Leeder

    Children's Mercy Hospital, United States

    19 publications · 2.2K citations

    17

    h-index

  3. AL
    Adrián LLerena

    Universidad de Extremadura, Spain

    20 publications · 759 citations

    16

    h-index

  4. MS
    Matthias Schwab

    Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Germany

    14 publications · 1.5K citations

    14

    h-index

  5. PD
    Pedro Dorado

    Universidad de Extremadura, Spain

    13 publications · 510 citations

    13

    h-index

1–5 of 2.7K

Institutions

917

  1. Children's Mercy Hospital

    Kansas City, United States

    23 h-index

    105 publications

    13.7K citations

  2. Karolinska Institutet

    Stockholm, Sweden

    21 h-index

    86 publications

    6.3K citations

  3. Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology

    Stuttgart, Germany

    19 h-index

    108 publications

    10.3K citations

  4. University of Missouri–Kansas City

    Kansas City, United States

    18 h-index

    78 publications

    8K citations

  5. Universidad de Extremadura

    Badajoz, Spain

    16 h-index

    63 publications

    3.1K citations

  6. Indiana University – Purdue University Indianapolis

    Indianapolis, United States

    15 h-index

    80 publications

    9.3K citations

  7. University of Michigan

    Ann Arbor, United States

    12 h-index

    58 publications

    7.1K citations

  8. Karolinska University Hospital

    Stockholm, Sweden

    12 h-index

    30 publications

    2.1K citations

1–8 of 917

Venues

  1. Clinical Pharmacology & Therapeutics

    CPT · 54 publications · 6K citations

    36

    h-index

  2. Pharmacogenetics

    35 publications · 2.3K citations

    28

    h-index

  3. British Journal of Clinical Pharmacology

    BJCP · 26 publications · 1.8K citations

    22

    h-index

  4. European Journal of Clinical Pharmacology

    21 publications · 866 citations

    19

    h-index

  5. Pharmacogenomics

    23 publications · 699 citations

    16

    h-index

1–5