MTHFR C677T and A1298C variant genotypes and the risk of microsatellite instability among Iranian colorectal cancer patients

A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer.

C. Richard Boland, Stephen N. Thibodeau, Stanley R. Hamilton et al. · PubMed · 1998 · 4.1K citations

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A Second Common Mutation in the Methylenetetrahydrofolate Reductase Gene: An Additional Risk Factor for Neural-Tube Defects?

N.M.J. van der Put, F. Gabreëls, E M Stevens et al. · The American Journal of Human Genetics · 1998 · 1.6K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

A Second Genetic Polymorphism in Methylenetetrahydrofolate Reductase (MTHFR) Associated with Decreased Enzyme Activity

Ilan Weisberg, Pamela V. Tran, Benedicte Christensen et al. · Molecular Genetics and Metabolism · 1998 · 1.3K citations

Life Sciences, Genetics, Molecular Genetics +11

Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer.

Jing Ma, Meir J. Stampfer, Edward L. Giovannucci et al. · PubMed · 1997 · 794 citations

Medicine, Genetics, Oncology +16

Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer

Lanlan Shen, Minoru Toyota, Yutaka Kondo et al. · Proceedings of the National Academy of Sciences · 2007 · 554 citations · Full text

Medicine, Genetics, Oncology +17