CpG island methylator phenotype in colorectal cancer

Minoru Toyota, Nita Ahuja, Mutsumi Ohe-Toyota, +3

Proceedings of the National Academy of Sciences

Tumor BiologyAberrant MethylationMedicineGeneticsEpigenetic Change +10

Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer

Hiromu Suzuki, D. Neil Watkins, Kam-Wing Jair, +13

Nature Genetics

Sfrp GenesRadiation OncologyMedicineEpigenetic InactivationColorectal Cancer +7

Epigenetic Silencing of <i>MicroRNA-34b/c</i> and <i>B-Cell Translocation Gene 4</i> Is Associated with CpG Island Methylation in Colorectal Cancer

Minoru Toyota, Hiromu Suzuki, Yasushi Sasaki, +4

Cancer Research

Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer

Lanlan Shen, Minoru Toyota, Yutaka Kondo, +8

Proceedings of the National Academy of Sciences

EngineeringEpigenetic ChangeGeneticsDna MethylationPathology +15

Analysis of adenomatous polyposis coli promoter hypermethylation in human cancer.

Manel Esteller, Andrew B. Sparks, Minoru Toyota, +9

PubMed

Epigenetic ChangeGeneticsMolecular BiologyPathologyCancer Biology +19

Distinct genetic profiles in colorectal tumors with or without the CpG island methylator phenotype

Minoru Toyota, Mutsumi Ohe-Toyota, Nita Ahuja, +1

Proceedings of the National Academy of Sciences

Identification of differentially methylated sequences in colorectal cancer by methylated CpG island amplification.

Minoru Toyota, Coty Ho, Nita Ahuja, +5

PubMed

EngineeringEpigenetic ChangeGeneticsDna MethylationPathology +17

<i>Fusobacterium</i> in Colonic Flora and Molecular Features of Colorectal Carcinoma

Tomomitsu Tahara, Eiichiro Yamamoto, Hiromu Suzuki, +12

Cancer Research

Hypermethylation of multiple genes in pancreatic adenocarcinoma.

Takashi Ueki, Minoru Toyota, Taylor A. Sohn, +4

PubMed

Epigenetic ChangeGeneticsDna MethylationPathologyEpigenetics +16

Upregulation of miR-196a and <i>HOTAIR</i> Drive Malignant Character in Gastrointestinal Stromal Tumors

Takeshi Niinuma, Hiromu Suzuki, Masanori Nojima, +22

Cancer Research