Concepedia

Microsatellite Instability Detection

Microsatellite Instability Detection is a computational method in genomic analysis that identifies aberrations in repetitive DNA sequences by comparing allelic patterns between tumor and normal tissues to infer underlying mismatch repair deficiency.

741

Publications

54K

Citations

5.4K

Authors

1.3K

Institutions

Publications per year

2017–2026

188

Parents

Publications

741

A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer.

C. Richard Boland, Stephen N. Thibodeau, Stanley R. Hamilton et al. · PubMed · 1998 · 4.1K citations

, , +17

Deep learning can predict microsatellite instability directly from histology in gastrointestinal cancer

Jakob Nikolas Kather, Alexander T. Pearson, Niels Halama et al. · Nature Medicine · 2019 · 1.4K citations · Full text

, , +16

Pembrolizumab versus chemotherapy for microsatellite instability-high or mismatch repair-deficient metastatic colorectal cancer (KEYNOTE-177): final analysis of a randomised, open-label, phase 3 study

Luis A. Díaz, Kai‐Keen Shiu, Tae‐Won Kim et al. · The Lancet Oncology · 2022 · 894 citations · Full text

, , +14

MSIsensor: microsatellite instability detection using paired tumor-normal sequence data

Beifang Niu, Kai Ye, Qunyuan Zhang et al. · Bioinformatics · 2013 · 872 citations · Full text

, , +17

Feasibility of Screening for Lynch Syndrome Among Patients With Colorectal Cancer

Heather Hampel, Wendy L. Frankel, Edward W. Martin et al. · Journal of Clinical Oncology · 2008 · 871 citations

, , +17

1–5 of 741

Authors

5.4K

  1. DS
    David Sidransky

    Johns Hopkins University, United States

    10 publications · 6K citations

    10

    h-index

  2. SO
    Shinya Oda

    Kyushu University, Japan

    10 publications · 339 citations

    10

    h-index

  3. SN
    Stephen N. Thibodeau

    Mayo Clinic, United States

    10 publications · 5.9K citations

    10

    h-index

  4. PQ
    Philip Quirke

    University of Leeds, United Kingdom

    10 publications · 1.1K citations

    10

    h-index

  5. AD
    Alex Duval

    Inserm, France

    10 publications · 1.3K citations

    10

    h-index

1–5 of 5.4K

Institutions

1.3K

  1. Inserm

    Paris, France

    25 h-index

    180 publications

    14.9K citations

  2. Johns Hopkins University

    Baltimore, United States

    19 h-index

    81 publications

    26.4K citations

  3. Heidelberg University

    Heidelberg, Germany

    16 h-index

    90 publications

    18.5K citations

  4. The University of Texas MD Anderson Cancer Center

    Houston, United States

    16 h-index

    81 publications

    6.5K citations

  5. Johns Hopkins Medicine

    Baltimore, United States

    16 h-index

    68 publications

    12.9K citations

  6. Sorbonne Université

    Paris, France

    16 h-index

    118 publications

    9.9K citations

  7. University of Leeds

    Leeds, United Kingdom

    15 h-index

    69 publications

    8.1K citations

  8. Memorial Sloan Kettering Cancer Center

    New York, United States

    14 h-index

    88 publications

    7.5K citations

1–8 of 1.3K

Venues

  1. PubMed

    Repository · 78 publications · 9.8K citations

    43

    h-index

  2. International Journal of Cancer

    24 publications · 1.3K citations

    21

    h-index

  3. British Journal of Cancer

    BJC · 22 publications · 1.4K citations

    20

    h-index

  4. Journal of Clinical Oncology

    20 publications · 4.5K citations

    17

    h-index

  5. Journal of Molecular Diagnostics

    JMD · 14 publications · 2.1K citations

    14

    h-index

1–5