Concepedia

Effects of Fibrates on Metabolism of Statins in Human Hepatocytes

Thomayant Prueksaritanont, Cuyue Tang, Yue Qiu, Lillian Mu, Raju Subramanian, Jiunn H. Lin

Drug Metabolism and Disposition · 2002 · 324 citations · 20 references

DOI

Concepts

References

20

Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.

Deborah J. Newton, R W Wang, Anthony Y.H. Lu · Drug Metabolism and Disposition · 1995 · 606 citations

, , +17

Preclinical and clinical pharmacology of rosuvastatin, a new 3-hydroxy- 3-methylglutaryl coenzyme A reductase inhibitor11CRESTOR is a trademark, the property of AstraZeneca PLC. Research discussed in this article was supported by AstraZeneca.

Fergus McTaggart, Linda K. Buckett, Robert G. Davidson et al. · The American Journal of Cardiology · 2001 · 415 citations

, , +8

Selective biotransformation of taxol to 6 alpha-hydroxytaxol by human cytochrome P450 2C8.

Atiqur Rahman, Ken Korzekwa, James Grogan et al. · PubMed · 1994 · 391 citations

, , +17

Glucuronidation of Statins in Animals and Humans: A Novel Mechanism of Statin Lactonization

Thomayant Prueksaritanont, Raju Subramanian, Xiaojun Fang et al. · Drug Metabolism and Disposition · 2002 · 346 citations

, , +13

Mechanistic Studies on Metabolic Interactions between Gemfibrozil and Statins

Thomayant Prueksaritanont, Jamie J. Zhao, Bennett Ma et al. · Journal of Pharmacology and Experimental Therapeutics · 2002 · 288 citations

, , +14