Deborah J. Newton

Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.

Deborah J. Newton, R W Wang, Anthony Y.H. Lu · Drug Metabolism and Disposition · 1995 · 606 citations

Human Cytochrome P-450 3A4: In Vitro Drug-Drug Interaction Patterns Are Substrate-Dependent

Regina W. Wang, Deborah J. Newton, Nini Liu et al. · Drug Metabolism and Disposition · 2000 · 239 citations

Human cytochrome P450 3A4-catalyzed testosterone 6 beta-hydroxylation and erythromycin N-demethylation. Competition during catalysis.

Regina W. Wang, Deborah J. Newton, T D Scheri et al. · PubMed · 1997 · 141 citations

Erythromycin N-demethylation, Aldo-keto Reductase, Chemical Biology +17

Characterization of Mice Lacking the Multidrug Resistance Protein Mrp2 (Abcc2)

Xiaoyan Chu, John R. Strauss, Michele A. Mariano et al. · Journal of Pharmacology and Experimental Therapeutics · 2006 · 141 citations

CYTOCHROME P450 3A4 IS THE MAJOR ENZYME INVOLVED IN THE METABOLISM OF THE SUBSTANCE P RECEPTOR ANTAGONIST APREPITANT

Rosa I. Sánchez, Regina W. Wang, Deborah J. Newton et al. · Drug Metabolism and Disposition · 2004 · 112 citations