Concepedia

Small-molecule inhibitors of the AAA+ ATPase motor cytoplasmic dynein

Ari J. Firestone, Joshua S. Weinger, María Maldonado, Kari Barlan, Lance D. Langston, Vladimir I. Gelfand, Tarun M. Kapoor, James Chen

Nature · 2012 · 415 citations · 25 references

DOIFull text

Open access

Concepts

References

25

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

Jussi Taipale, James Chen, Michael K. Cooper et al. · Nature · 2000 · 1.3K citations

, , +9

Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts

Rebecca Heald, Régis Tournebize, Thiemo Blank et al. · Nature · 1996 · 989 citations

, , +16

Cilia and Hedgehog responsiveness in the mouse

Danwei Huangfu, Kathryn V. Anderson · Proceedings of the National Academy of Sciences · 2005 · 825 citations · Full text

, , +17

A Complex of NuMA and Cytoplasmic Dynein Is Essential for Mitotic Spindle Assembly

Andreas Merdes, Kasra X. Ramyar, Janet D. Vechio et al. · Cell · 1996 · 576 citations · Full text

, , +15

The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins

Eric W. Humke, Karolin V. Dorn, Ljiljana Milenković et al. · Genes & Development · 2010 · 449 citations · Full text

, , +16