Lance D. Langston

Small-molecule inhibitors of the AAA+ ATPase motor cytoplasmic dynein

Ari J. Firestone, Joshua S. Weinger, María Maldonado et al. · Nature · 2012 · 402 citations · Full text

Biochemistry, Natural Sciences, Macromolecular Machine +8

Mechanism of asymmetric polymerase assembly at the eukaryotic replication fork

Roxana E. Georgescu, Lance D. Langston, Nina Y. Yao et al. · Nature Structural & Molecular Biology · 2014 · 196 citations

Asymmetric Polymerase Assembly, Protein Assembly, Natural Sciences +4

CMG helicase and DNA polymerase ε form a functional 15-subunit holoenzyme for eukaryotic leading-strand DNA replication

Lance D. Langston, Dan Zhang, Olga Yurieva et al. · Proceedings of the National Academy of Sciences · 2014 · 175 citations · Full text

Reconstitution of a eukaryotic replisome reveals suppression mechanisms that define leading/lagging strand operation

Roxana E. Georgescu, Grant D. Schauer, Nina Y. Yao et al. · eLife · 2015 · 140 citations · Full text

Translesion DNA polymerases remodel the replisome and alter the speed of the replicative helicase

Chiara Indiani, Lance D. Langston, Olga Yurieva et al. · Proceedings of the National Academy of Sciences · 2009 · 122 citations · Full text

Genome Instability, Specialized Translesion Dna, Biochemistry +10