Polyion complex micelles entrapping cationic dendrimer porphyrin: effective photosensitizer for photodynamic therapy of cancer

A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs.

Yasuhiro Matsumura, Hiroshi Maeda · PubMed · 1986 · 6.8K citations

Medicine, Oncology, Pharmacology +12

Basic principles of photodynamic therapy

Ian J. MacDonald, Thomas J. Dougherty · Journal of Porphyrins and Phthalocyanines · 2001 · 1.4K citations

Engineering, Dermatology, Ophthalmology +13

Dendrimers:

N Malik, Ruedeekorn Wiwattanapatapee, Rainer Klopsch et al. · Journal of Controlled Release · 2000 · 1.2K citations

Efficient transfer of genetic material into mammalian cells using Starburst polyamidoamine dendrimers.

Jolanta F. Kukowska‐Latallo, Anna U. Bielinska, James M. Johnson et al. · Proceedings of the National Academy of Sciences · 1996 · 1K citations

Pharmacy, Biotechnology, Molecular Biology +17

Formation of Polyion Complex Micelles in an Aqueous Milieu from a Pair of Oppositely-Charged Block Copolymers with Poly(ethylene glycol) Segments

Atsushi Harada, Kazunori Kataoka · Macromolecules · 1995 · 836 citations

Natural Sciences, Chemistry, Materials Science +17