Hiroyuki Koyama

Preparation and Biological Characterization of Polymeric Micelle Drug Carriers with Intracellular pH-Triggered Drug Release Property:  Tumor Permeability, Controlled Subcellular Drug Distribution, and Enhanced in Vivo Antitumor Efficacy

Younsoo Bae, Nobuhiro Nishiyama, Shigeto Fukushima et al. · Bioconjugate Chemistry · 2004 · 732 citations

Pharmacy, Pharmaceutics, Pharmacology +17

<i>AtALMT1</i> , which encodes a malate transporter, is identified as one of several genes critical for aluminum tolerance in <i>Arabidopsis</i>

Owen A. Hoekenga, Lyza Maron, Miguel A. Piñeros et al. · Proceedings of the National Academy of Sciences · 2006 · 581 citations · Full text

Life Sciences, Plant Biology, Plant Sciences +12

Cyclic RGD-Linked Polymeric Micelles for Targeted Delivery of Platinum Anticancer Drugs to Glioblastoma through the Blood–Brain Tumor Barrier

Yutaka Miura, Tomoya Takenaka, Kazuko Toh et al. · ACS Nano · 2013 · 452 citations

Pharmacy, Oncology, Pharmaceutics +17

Zinc finger protein STOP1 is critical for proton tolerance in <i>Arabidopsis</i> and coregulates a key gene in aluminum tolerance

Satoshi Iuchi, Hiroyuki Koyama, Atsuko Iuchi et al. · Proceedings of the National Academy of Sciences · 2007 · 430 citations · Full text

Life Sciences, Plant Biology, Plant Sciences +14

Block Catiomer Polyplexes with Regulated Densities of Charge and Disulfide Cross-Linking Directed To Enhance Gene Expression

Kanjiro Miyata, Yoshinori Kakizawa, Nobuhiro Nishiyama et al. · Journal of the American Chemical Society · 2004 · 400 citations

Pharmacy, Biochemistry, Bioengineering +16